TP-7, Tuftsin analog · Evidence-based safety and harm-reduction overview.
| Also known as | TP-7, Tuftsin analog |
| Category | Nootropic |
| controlled_status | Unscheduled US (unapproved) |
| approval_status | Not FDA-approved; used clinically in Russia only |
| route | Nasal solution or subcutaneous injection |
| US legal status | Selank is a peptide developed in Russia and is not FDA-approved in the United States. It is sold as a research chemical and is not authorized for human consumption or medical use in the US. |
Selank is a synthetic peptide based on the immunomodulatory peptide tuftsin. It has been studied and used in Russia primarily for anxiety-related indications and is typically delivered as a nasal solution.
Research suggests Selank acts through enkephalin and GABAergic systems while also modulating monoamine neurotransmission. Studies indicate effects on anxiety centers in the brain and possible modulation of immune function, though detailed human mechanisms remain unclear and largely documented only in Russian preclinical work.
Selank was synthesized in Russia in the 1980s based on tuftsin, an immunomodulatory peptide. It has been studied and prescribed in Russia for anxiety, stress, and cognitive enhancement but remains largely unknown outside Russian medical practice and online nootropic communities.
Research on Selank is largely from Russian studies that report anxiolytic and possible cognitive effects, with proposed actions on enkephalins and GABAergic and monoaminergic systems. Studies suggest it may reduce anxiety in small trials, but independent, large-scale human research is limited, so the overall evidence remains preliminary and mixed.
Russian clinical practice typically uses intranasal or subcutaneous Selank at doses of 250-500 micrograms once or twice daily. Nasal administration protocols in studies vary, and commercial product dosing accuracy is uncertain.
This is general research/context information, not medical advice or a recommended protocol.
Selank interactions with other anxiolytic, nootropic, or psychiatric medications are essentially unstudied and should not be attempted without professional medical oversight.
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Compare testing optionsNo. It is not approved in the US and is sold only as a research chemical, not for human consumption.
No. It is a peptide studied for anxiolytic effects through different mechanisms, but its human evidence base is limited.
We do not provide dosing advice. Given its unapproved status and sparse safety data, consult a qualified clinician.
No. Selank is unapproved and unproven; anyone with anxiety disorders should work with a clinician using evidence-based treatments.
Russian reports suggest effects develop over days to weeks; there are no controlled human studies detailing onset or time-to-effect.
Long-term human safety data do not exist. Any use should be discussed with a medical professional and regularly reassessed.
Medical & legal disclaimer. This site is for informational and harm-reduction purposes only. It is not medical advice and is not a substitute for a licensed healthcare professional. The compounds discussed are largely not approved by the FDA for human use and many are sold strictly as research chemicals 'not for human consumption.' Nothing here is an endorsement to purchase, possess, or use any substance. Laws vary by jurisdiction. Always consult a qualified physician and follow the law where you live.
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