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Nootropic Moderate risk

Phenylpiracetam

Phenotropil, Carphedon, Fonturacetam · Evidence-based safety and harm-reduction overview.

Not medical advice. Phenylpiracetam is discussed here for informational and harm-reduction purposes only. We do not endorse use, and any dosing context is informational, not a protocol.
Also known asPhenotropil, Carphedon, Fonturacetam
CategoryNootropic
year_developed1980s
originRussian research
potency_relative_to_piracetamMore potent by weight, lower doses used
wada_statusProhibited
US legal statusPhenylpiracetam is not FDA-approved as a drug in the United States and is not a lawful dietary supplement ingredient; it is usually sold in a gray market labeled as a research chemical not for human consumption. It is on the World Anti-Doping Agency (WADA) prohibited list, so it is banned in regulated sport. It is a prescription medicine in some countries such as Russia.
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What is Phenylpiracetam?

Phenylpiracetam is a phenylated derivative of piracetam developed in Russia. The added phenyl group changes its properties and is associated with stimulant-like effects compared with piracetam. This modification was intended to create a more potent variant with a different mechanism and safety profile.

How it works

Phenylpiracetam is thought to work through effects on monoamine neurotransmission, particularly dopamine and norepinephrine systems, which may account for its stimulant-like profile. It may also share membrane-modulating properties with other racetams, though the phenyl group likely alters its binding profile. Mechanistic evidence in humans is limited and much comes from animal studies.

Background & history

Phenylpiracetam (also known as Phenotropil) was developed in Russia in the 1980s as a stimulant-like derivative of piracetam. It was marketed in Russia and some Eastern European countries for cognitive and physical performance enhancement. Its WADA ban reflects its use and effects in sports contexts.

What the research says

Research suggests phenylpiracetam has stimulant-like and possibly cognition-related effects in some studies, but much of the published work originates from a single region, is dated, or is of limited quality. Robust, independent human trials are scarce, so claims should be treated cautiously. Some studies focus on physical performance rather than cognition per se.

Reported effects

Dosing & administration (informational)

In studies, phenylpiracetam has been administered at oral doses ranging from approximately 100 to 600 milligrams daily, typically divided into multiple doses. Trial durations have varied from acute single-dose to chronic multi-week protocols. It is notably more potent by weight than piracetam.

This is general research/context information, not medical advice or a recommended protocol.

Safety & side effects

Drug & supplement interactions

Who should avoid it

How it is commonly combined

Phenylpiracetam has been studied with other compounds in older literature, but modern evidence for beneficial combinations is absent. Its stimulant profile makes stacking with other stimulants risky. Informational only.

Quality & harm reduction

Lab testing & harm-reduction tools

If you are going to research a compound, verifying identity and purity is the single most protective step. Independent analytical testing and sterile-handling supplies reduce risk.

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Frequently asked questions

Is phenylpiracetam banned in sports?

Yes. It is on the WADA prohibited list, so competitive athletes who use it risk testing positive and facing sanctions.

What dose is recommended?

We do not offer dosing guidance. Any use of an unapproved, stimulant-like compound should be discussed with a clinician first.

How does it differ from piracetam?

It has an added phenyl group and a more stimulant-like profile. Like piracetam, it is not FDA-approved or a lawful US supplement.

Is phenylpiracetam more potent than piracetam?

Yes. Phenylpiracetam is active at much lower doses than piracetam, making it notably more potent by weight.

Why is phenylpiracetam banned in sports?

Its stimulant-like effects on performance and alertness led to its inclusion on the WADA prohibited substances list.

References & further reading

  1. PubMed: phenylpiracetam stimulant cognition performance
  2. WADA prohibited substances list
  3. PubMed: monoamine effects racetams Russia

Medical & legal disclaimer. This site is for informational and harm-reduction purposes only. It is not medical advice and is not a substitute for a licensed healthcare professional. The compounds discussed are largely not approved by the FDA for human use and many are sold strictly as research chemicals 'not for human consumption.' Nothing here is an endorsement to purchase, possess, or use any substance. Laws vary by jurisdiction. Always consult a qualified physician and follow the law where you live.

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